5-Amino-1MQ 50mg
35,90 €
View the certificate of analysis and HPLC purity verification for this batch.
Description
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5-Amino-1MQ 50 mg
Research-grade lyophilized powder in a sterile glass vial. 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) — a key enzyme at the crossroads of NAD⁺ metabolism and cellular methylation balance.
Unlike the peptides in our catalog, 5-Amino-1MQ is a small molecule — a selective blocker of the enzyme NNMT. Because NNMT consumes both nicotinamide (the NAD⁺ precursor) and SAM (the universal methyl donor), inhibiting it lets researchers study two of the cell’s most important metabolic currencies at once.
Models exploring NNMT blockade and resulting shifts in NAD⁺ availability and SAM-cycle flux.
Diet-induced obesity models examining lipogenesis suppression and adipocyte metabolic reprogramming.
Laboratory work on cellular methylation burden, 1-methylnicotinamide levels and SAM-cycle imbalance.
Preclinical studies on NAD⁺-linked pathways in muscle regeneration and metabolic decline.
NOT FOR HUMAN OR VETERINARY USE · NOT A FOOD, SUPPLEMENT, COSMETIC OR MEDICINE · ALL CONTENT IS EDUCATIONAL ONLY

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